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Croote, D., Quake, S.R. Food allergen detection by mass spectrometry: the role of systems biology. npj Syst Biol Appl. 2016 Sep 29; 2:16022.

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Common carp Protein: Cyp c 1 | β-Parvalbumin

Isoform:

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 109 amino acids

MAFAGILNDADITAALQGCQAADSFDYKSFFAKVGLSAKTPDDIKKAFAVIDQDKSGFIEEDELKLFLQNFSAGARALTDAETKAFLKAGDSDGDGKIGVDEFAALVKA

UniProt: Q8UUS3   IUIS: Cyp c 1

Empirical Proteotypic Peptide Explorer:

This rose plot enables visualization of proteotypic peptides. Each colored rose petal corresponds to a peptide and is bounded by thin gray petals, which represent tryptic cut sites. The radial magnitude of each peptide corresponds to the number of publications which report it.

Hover over a rose petal with your mouse to see the peptide. Click on a rose petal to see the species specificity of that peptide and add it to your cart.


Sequence - 109 amino acids

MAFAGVLNDADITAALEACKAADSFNHKTFFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKAGARALTDGETKTFLKAGDSDGDGKIGVDEFTALVKA

UniProt: Q8UUS2   IUIS: Cyp c 1

Peptide Selector Tool

Explore peptide targets for mass spectrometry by adjusting the selection criteria below. Results from empirical and computational prediction tools have been aggregated for convenience.

Exclude:
Peptide Characteristics:

Minimum length:

Maximum length:

1 Peptide 2 Exp.3 ESP4 CONSeQ5
^ MAFAGILNDADITAALQGCQAADSFDYK S 0 0.383 0.05236
K AFAVIDQDK S 0 0.389 0.6142
K SGFIEEDELK L 0 0.436 0.60546
K LFLQNFSAGAR A 0 0.597 0.47208
R ALTDAETK A 0 0.23 0.4154
K AGDSDGDGK I 0 0.236 0.13786
K IGVDEFAALVK A 0 0.576 0.56652
^ MAFAGVLNDADITAALEACK A 0 0.565 0.11462
K AADSFNHK T 0 0.28 0.17708
K AFAIIDQDK S 0 0.378 0.52184
K SGFIEEDELK L 0 0.436 0.60546
K LFLQNFK A 0 0.32 0.19254
R ALTDGETK T 0 0.21 0.2659
K AGDSDGDGK I 0 0.236 0.13786
K IGVDEFTALVK A 0 0.562 0.5675

1 Previous amino acid (^ = Start of protein)

2 Next amino acid ($ = End of protein)

3 Exp. = Number of publications in which this peptide has been reported experimentally

4 ESP = ESP Predictor. Fusaro VA, et al. Nat Botechnol 2009; 27(2): 190-198. doi

5 CONSeQ = CONSeQuence. Eyers CE, et al. Mol Cell Proteomics 2011; 10(11). doi

Underline: Peptide occurs within the first 20 amino acids from the start of the protein. Use caution as the protein may contain a cleaved signaling sequence.

Strike-through: Peptide is present in a protein from another allergen species and is thus nonspecific.

 

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